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Projects & Publications

Projects

  1. Project I -- Exposure: Detection, Fate and Transport of Agents
    Charles P. Gerba, University of Arizona

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  2. Project II -- Infectious Disease Models for Assessing Microbial Risks and Developing Control Strategies
    Joseph N.S. Eisenberg, University of Michigan-Ann Arbor

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  3. Project III -- Dose Response Assessment
    Charles N. Haas, Drexel

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  4. Project IV -- The Assessment-analysis Interface
    Patrick Gurian, Drexel

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  5. Project V -- Knowledge Management, Transfer, and Learning
    Rosina Weber, Drexel

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Recent Publications

(Peer reviewed journals)

  • Greenberg, D. L., J. D. Busch, D. M. Wagner and P. Keim (2010). "Identifying experimental surrogates for Bacillus anthracis spores: a review." Investigative Genetics 1(4).
  • Gunawardena, S., R. Weber and D. E. Agosto (2010). "Finding that Special Someone: Modeling Collaboration in an Academic Context." Journal of Education for Library and Information Science 51(4).
  • Hong, T., P. L. Gurian and N. Ward (2010). "Setting Risk-Informed Environmental Standards for Bacillus Anthracis Spores." Risk Analysis 30(10): 1602-1622.
  • Huang, Y. and C. N. Haas (in press). "Quantification of the relationship between bacterial kinetics and host response for monkeys exposed to aerosolized Francisella tularensis." Applied and Environmental Microbiology.
  • Huang, Y., T. Hong, T. A. Bartrand, P. L. Gurian, C. N. Haas, R. Liu and S. B. Tamrakar (2010). "How Sensitive Is Safe? Risk-Based Targets for Ambient Monitoring of Pathogens." IEEE Sensors Journal 10(3): 668-673.
  • Mayer, B. T., J. S. Koopman, E. L. Ionides, J. Pujol and J. N. S. Eisenberg (in press). "A dynamic doseresponse model to account for exposure patterns in risk assessment: a case study in inhalation anthrax." Journal of the Royal Society Interface.
  • Mitchell-Blackwood, J., P. L. Gurian and C. O’Donnell (in press). "Finding Risk-based Switchover Points for Response Decisions for Environmental Exposure to Bacillus anthracis" submitted to Human and Ecological Risk Assessment." Human and Ecological Risk Assessment.
  • Razzolini, M.T.P., Weir, M.H. Matte, M.H., Matte, G.R., Fernandes, L.N. Rose, J.B. (accepted) Risk of Giardia infection for drinking water and bathing in a peri-urban area in São Paulo, Brazil. International Journal of Environmental Health Research
  • Romero-Gomez, P., K. E. Lansey and C. Y. Choi (in press). "Impact of an incomplete solute mixing model on sensor network design." Hydroinformatics.
  • Spicknall, I., J. Koopman, M. Nicas, J. Pujol, L. Sheng and J. Eisenberg (2010). "Informing Optimal Environmental Influenza Interventions: How the Host, Agent, and Environment Alter Dominant Routes of Transmission." PLoS Computational Biology 6(10).
  • Tamrakar, S. B., A. Haluska, C. N. Haas and T. A. Bartrand (in press). "Dose-Response Model ofCoxiella burnetii(Q Fever)." Risk Analysis.
  • Zelner, J., A. A. King, C. L. Moe and J. N. S. Eisenberg (2010). "How Infections Propagate After Point Source Outbreaks: An Analysis of Secondary Norovirus Transmission." Epidemiology 21(5): 711-718.

(Theses / Dissertations)

  • Pedro Romero-Gomez, University of Arizona, 2010. Doctoral Dissertation. Transport phenomena in drinking water systems. Supervised by Professor Christopher Choi.
  • Jade Mitchell-Blackwood, Drexel University, 2010. Using Analytic Models to Address Uncertainty and Establish Thresholds for Risk-Based Responses to Pathogenic Agents in the Environment. Doctoral Dissertation. Supervised by Professor Patrick Gurian.
  • Yin Huang, Drexel University, 2010. Doctoral Dissertation. Incorporating Time to Response into Dose-Response Models Used in Quantitative Microbial Risk Assessment. Supervised by Professor Charles Haas.
  • Ian Solon, Drexel University, 2010. Master Thesis. The extraction of a B. anthracis Surrogate from Pleated HVAC Filters. Supervised by Professor Patrick Gurian.

Earlier Publications

(Peer reviewed journals)

  • Corella-Barud, V., K.D. Mena, S.G. Gibbs, P.L. Gurian, and A. Barud. (2009). Evaluation of Neighborhood Treatment Systems for Potable Water Supply. International Journal of Environmental Health Research, 19(1):49-58
  • Durham D.P.and Casman, E. A. (In Press) Threshold Conditions for Bubonic Plague Persistence in Urban Rats. Risk Analysis.
  • Herzog AB, McLennan SD, Pandey AK, Gerba CP, Haas CN, Rose JB, Hashsham SA.(2009). Implications of Limits of Detection of Various Methods for Bacillus anthracis in Computing Risk to Human Health. Applied Environmental Microbiology. 75:6331-6339
  • Huang, Y., Bartrand, T.A., Haas, C.N. and Weir M.H. (2009) Incorporating Time Post Inoculation into a Dose-Response Model of Yersinia pestis in Mice. Journal of Applied Microbiology. 107(3):727-735.
  • Huang, Y. and Haas, C.N. (2009) Time-dose-response Models for Microbial Risk Assessment. Risk Analysis. 29(5): 648-661.
  • Huang, Y., Hong, T., Bartrand, T.A., Gurian, P.L., Haas, C.N., Liu, R., and Tamrakar, S.B. (2009) How Sensitive Is Safe? Risk-Based Targets for Ambient Monitoring of Pathogens. IEEE Sensors Journal. Accepted for publication.
  • Huang, Y., Hong, T., Bartrand, T.A., Gurian, P.L., Haas, C.N., Liu, R., and Tamrakar, S.B. (2009) How Sensitive Is Safe? Risk-Based Targets for Ambient Monitoring of Pathogens. IEEE Sensors Journal. Accepted for publication.
  • Jones, R.M., Masago, Y., Bartrand, Haas, C.N., Nicas, M., and J.B. Rose. (2009) Characterizing the risk of infection from Mycobacterium tuberculosis in commercial passenger aircraft using quantitative microbial risk assessment. Risk Analysis. 29, page 355.
  • Jones R. and Nicas, M, (2009) Experimental Determination of supermicrometer particle fate subsequent to a point release within a room under natural and forced mixing. Aerosol Science and Technology. 43: 921-938.
  • Sinclair, R., Gomez, P.R., Choi, C.Y., Gerba, C.P. (2009) Assessment of MS-2 phage and salt tracers to characterize axial dispersion in water distribution systems. Journal of Environmental Science and Health. 44: 963-971.
  • Weir M.H., Haas, C.N. (In Press) Quantifying the Effect of Age on the Dose Response of Variola majorin Suckling Mice. Human and Ecological Risk Assessment.
  • Sinclair, R., S. A. Boone, D. Greenberg, P. Keim, and C. P. Gerba. 2008. Persistence of Category A select agents in the environment. Appl. Environ. Microbiol. 74:555-563. Publisher's Site
  • Romero-Gomez, P., C. K. Ho, and C. Y. Choi. 2008. Mixing at Cross Junctions in Water Distribution Systems – Part I. A Numerical Study. ASCE Journal of Water Resources Planning and Management134(3):284-294. Abstract | Publisher's Site
  • Austin, R. G., B. van Bloemen Waanders, S. McKenna and C. Y. Choi. 2008. Mixing at Cross Junctions in Water Distribution Systems – Part II. An Experimental Study. ASCE Journal of Water Resources Planning and Management 134(3):295-302. Abstract | Publisher's Site
  • Masago, Y., T. Shibata, and J. B. Rose. 2008. Bacteriophage P22 and Staphylococcus aureus Attenuation on Nonporous Fomites as Determined by Plate Assay and Quantitative PCR. Applied and Environmental Microbiology 74(18):5838-5840. Abstract | Publisher's Site
  • Bartrand, T. A., M. H. Weir, and C. N. Haas. 2008. Dose-Response Models for Inhalation of Bacillus anthracis Spores: Interspecies Comparisions. Risk Analysis 28(4):1115-1124. Abstract | Publisher's Site
  • Tamrakar, S.B. and C. N. Haas.  2008.  Dose-Response Model for Lassa Virus.  Human and Ecological Risk Assessment 14(4): 742-752. Abstract | Publisher's Site
  • Tamrakar, S.B. and C. N. Haas. 2008. Dose-Response Model for Burkholderia pseudomallei (melioidosis). Journal of Applied Microbiology 105(5):1361-1371. Abstract | Publisher's Site
  • Casman, E. A. and B. Fischhoff. 2008. Risk Communication Planning for the Aftermath of a Plague Bioattack. Risk Analysis 28(5): 1327-1342. Abstract | Publisher's Site
  • Choi, C. Y., I. Song, and P. Romero-Gomez. Solute Transport in a Pressurized Pipe Network with Multiple Cross Junctions. ASCE Journal of Hydraulic Engineering (Currently under Review).
  • Pujoli, J. M., J. E. Eisenberg, C. N. Haas, and J. S. Koopman. The Effect of Ongoing Exposure Dynamics in Dose Response Relationships. PLoS Computational Biology (Currently under Review).
  • Eisenberg, J. E. A Dynamic Dose-Response Model for Modelling Infection Transmission. Journal of the Royal Society Interface (Currently under Review).
  • Li, S. Dynamics and Control of Infections Transmitted from Person to Person Through the Environment. American Journal of Epidemiology (Currently under Review).
  • Weir, M. H. and C. N. Haas. Quantification of the Effects of Age on the Dose Response of Variola major in Suckling Mice.  Human and Ecological Risk Assessment (Currently under Review).
  • Huang, Y., T. A. Bartrand, and C. N. Haas. Incorporating time post inoculation into a dose response model for Yersinia pestis in mice. Journal of Applied Microbiology (Currently under Review).
  • Huang, Y. and C. N. Haas. Time-to-dose-response Models for Microbial Risk Assessment. Risk Analysis (Currently under Review).
  • Huang, Y., T. Hong, T. Bartrand, P. L. Gurian, C. N. Haas, R. Liu, and S. Tamrakar. How Sensitive is Safe? Risk-based Targets for Ambient Monitoring of Pathogens. IEEE Sensors Journal (Currently under Review).
  • Durham, D. and E. Casman. Threshold Conditions for Bubonic Plague Persistence in Urban Rats. PNAS (Currently under Review).
  • Boone, S. A. and C. P. Gerba 2007. The significance of fomites in the spread of respiratory and gastrointestinal disease. Applied and Environmental Microbiology, 73:1687-1696.
  • Weber, R. O. "Addressing Failure Factors in Knowledge Management," (2007). Electronic Journal of Knowledge Management, 5(3): pp. 333-346. Online: http://www.ejkm.com/volume-5/v5-i3/Weber.pdf
  • Weber, R. O. & Gunawardena, S. Designing Multifunctional Knowledge Management Systems. Accepted for publication in the proceedings of the Hawaii International Conference on System Sciences (HICSS-41), January 2008.
  • Weber, R. O., Gunawardena, S. & Proctor, J. M. Generating Reports from Case-Based Knowledge Artifacts. In D. Wilson & G. Sutcliffe (Eds.), Proceedings of the Twentieth International Florida Artificial Intelligence Research Society Conference (FLAIRS 2007) Menlo Park CA: AAAI Press.
  • Romero, P., C. K. Ho, and C. Y. Choi, 2007, Mixing at Cross Junctions in Water Distribution Systems – Part I. A Numerical Study, ASCE Journal of Water Resources Planning and Management (in press).
  • Austin, R. G., B. van Bloemen Waanders, S. McKenna and C. Y. Choi, 2007, Mixing at Cross Junctions in Water Distribution Systems – Part II. An Experimental Study, ASCE Journal of Water Resources Planning and Management (in press).
  • Pujol JM, Eisenberg JNS1, Haas CN; Koopman JS. 2007. The Effect of Ongoing Exposure Dynamics in Dose Response Relationships. Submitted to PNAS.
  • Sinclair, R., S. Boone, C. P. Gerba, D. Greenberg, D. Wagner and P. Keim. 2007. Persistence of select agents category A in the environment. Accepted Applied and Environmental Microbiology.
  • Verónica Corella-Barud, Kristina D. Mena, Shawn G. Gibbs, Patrick L. Gurian, and Alberto Barud. 2007. Evaluation of Neighborhood Treatment Systems for Potable Water Supply, submitted to International Journal of Environmental Health Research.
  • Haas et al. Dose-Response Models for Inhalation of Bacillus anthracis Spores: Interspecies Comparisons. Risk Analysis (Currently under Review)
  • Haas et al.Quantification of the Effects of Age on Dose Response of Variola major in Suckling Mice. Risk Analysis. (Currently under Review)
  • Haas et al.Dose Response Model for Lassa Virus. International Journal of Human Ecology & Risk Assessment (In Press)

(Peer Reviewed Proceedings)

  • Gunawardena, S., & Weber, R. (2009). Discovering Patterns of Collaboration for Recommendation. In Proceedings 22th International FLAIRS Conference, FLAIRS`09. AAAI Press, Menlo Park, California, 2009.
  • Gunawardena, S., & Weber, R. Paper presented at FLAIRS conference. (2009) Discovering Patterns of Collaboration for Recommendation. Proceedings: 22nd International FLAIRS Conference, FLAIRS`09. AAAI Press, Menlo Park, California, 2009.
  • Weber, R. O., S. Gunawardena, and C. MacDonald. 2008. Horizontal Case Representation. In: Advances in Case-Based Reasoning: Proceedings of the European Conference on Case-Based Reasoning. Althoff, K.-D., R. Bergmann, M. Minor, and A. Hanft, eds. pp. 548-561. Springer, Berlin / Heidelberg. Abstract | Publisher's Site
  • Weber, R. O. and S. Gunawardena. 2008. Designing Multifunctional Knowledge Management Systems. Proceedings of the 41st Annual Hawaii International Conference on System Sciences (HICSS-41):368-377. Abstract | Publisher's Site
  • Weber, R. O., S. Gunawardena, and G. Abraham 2008. Representing and Retrieving Knowledge Artifacts. In: Proceedings of the 7th International Conference on Practical Aspects of Knowledge Management (PAKM). T. Yamagchi ed. pp. 86-97. Springer-Verlag, Berlin / Heidelberg (In press).

(Book Chapters)

  • Pepper, I. L., C. Y. Choi, and C. P. Gerba. Microorganisms and bioterrorism. In: Environmental Microbiology. R. M. Maier, I. L. Pepper and C. P. Gerba, eds. pp. 565-574. Academic Press, San Diego.

(Theses / Dissertations)

  • Ms. Surakshya Dhakal, University of California Berkeley, 2009 Masters Thesis. Exploring the Relationships between Time-to-Mixing, Turbulence Intensity, and the Turbulent Diffusion Coefficient. Supervised by Professor Mark Nicas.
  • Tao Hong, Drexel University, 2009 Masters Thesis. Estimating risk of exposure to Bacillus anthracis based on environmental concentrations. Supervised by Patrick Gurian
  • Mark H. Weir, Drexel University, 2009. Doctoral Dissertation. Development of a Physiologically Based Pathogen Transport and Kinetics Model for Inhalation of Bacillus anthracis spores. Supervised by Charles N. Haas
  • Henley, J. B. 2008. Thesis for Master of Science. Determining the Inactivation Rates of Viruses on Indoor Surfaces. College of Agriculture and Life Sciences, Department of Soil, Water, and Environmental Science, University of Arizona.
  • Herzog, A. 2008. Thesis for Master of Engineering. Factors to Consider in the Evaluation of Risk at the Environmental Detection Limit. Center for Microbial Ecology, Department of Civil and Environmental Engineering, Michigan State University
  • Jones, R. M. 2008. Dissertation for Doctor of Philosophy. Experimental Evaluation of a Markov Model of Contamination Transport in Indoor Experiments with Application to Tuberculosis Transmission in Commercial Passenger Aircraft.  School of Public Health, Division of Environmental Health Sciences, University of California, Berkeley.

(Un-refereed documents)

  • White Paper Submitted in Support of the Physiologic Assessment of Microbial Effects (PhAME) Project.
  • White-Paper was submitted to USACCHPM and is currently pending security clearance for public release of the information. Jade Mitchell-Blackwood and Patrick L. Gurian, Development of Dose-Response Curves for Bacillus anthracis (Inhalation Anthrax) Using a Bayesian Approach on Historic Data.
  • White Paper Submitted in Support of the Physiologic Assessment of Microbial Effects (PhAME) Project, Limited Distribution through the U.S. Army Center for Health Promotion and Preventive Medicine, Environmental Health Risk Assessment Program (MCHB-TS-REH), Aberdeen Proving Ground, Maryland (2008).
  • Masago, Y, Jones, R, Bartrand, TA, Haas, CN, Rose, JB.  2008.  Estimates of risk associated with a tuberculosis patient and air travel. CAMRA TB Alert Report.
  • Rose, J. B., C. N. Haas, P. L. Gurian, and J. S. Koopman. 2008. Instruction manual for quantitative microbial risk assessment (QMRA). CAMRA 3rd QMRA Summer Institute, Michigan State University, East Lansing, MI.
  • Herzog, A., C. Rodriguez, K. Enger, M. Milbrath, O. Bucher, P. Okelo, S. Luster-Teasley, and Y. Huang. 2008. Risk Assessment on Anthrax release in IRS Building. Group A Case Study: CAMRA 3rd QMRA Summer Institute, Michigan State University, East Lansing, MI.
  • Pandey, A., W. Betacourt, A. Baynton, A. Wright, K. Bush, S. Khan, K. Shaw, A. Coulliette. 2008. Adventure Vacations: Leaving Norovirus at the Dock: A QMRA Assessment of Norovirus Outbreaks on Houseboats. Group B Case Study: CAMRA 3rd QMRA Summer Institute, Michigan State University, East Lansing, MI.
  • Mendoza-Sanchez, I., F. Simmons, C. O’Donnell, M. Sato, A. Rajić, B. Mayer, A. Jenkins, J. B. Rose, and G. Medema. Tularemia in Water: A Quantitative Microbial Risk Assessment. Group C Case Study: CAMRA 3rd QMRA Summer Institute, Michigan State University, East Lansing, MI.
  • Gurian, P., I. Young, M. T. Pepe Razzolini, R. Johnson, B. Schmidt, C. Flemming, T. Hong, and A. Smith. Risk Assessment for H5N1 Influenza A: Border Inspection of Smuggled Goods Exposure. Group D Case Study: CAMRA 3rd QMRA Summer Institute, Michigan State University, East Lansing, MI.
  • Shibata, T., Gurian, P, Rose JB., Haas, CN., Choi, C., Nicas, M., and Koopman, J., 2007. Instruction manual for quantitative microbial risk assessment (QMRA). CAMRA 2nd QMRA Summer Institute, Michigan State University, East Lansing, MI.

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